A combination of tretinoin and azelaic acid is often used to treat skin concerns including acne and hyperpigmentation, improving texture and brightening skin in general. They both have antioxidant, anti-inflammatory, and antibacterial properties but, unlike niacinamide, azelaic acid also acts as a mild exfoliant. While niacinamide doesnt have too many side effects, tretinoin can come along with a few. Holy Jeezz!, It was a bomb!. Niacinamide offers a ton of different benefits for the skin and can be used no matter what your skin type or skin concerns. Azelaic acid is a skincare ingredient found in wheat and barley, with antibacterial and anti-inflammatory properties that help keep skin clear. The tretinoin and niacinamide order is important when using these ingredients together to get the best results and prevent any irritation. Side effects. If you have any concerns about your health, consult a qualified healthcare professional. Pro-Vitamin B5 is a goodie that moisturises the skin, has anti-inflammatory, skin protecting and wound healing properties. If youre wondering should you use niacinamide or tretinoin first, the answer will depend on your products! Paula's Choice RESIST Anti-Aging Clear Skin Hydrator (see my review here) Tretinoin 0.1% cream ; METHOD: So, if you want to use this combination, I strongly advise you should start from lower concentration for the sake of your skins moisture-barrier, (example: 0.05% tretinoin and 10% azelaic acid). If youve heard the term retinoid and thought it sounded similar to retinol, youre right! Azelaic acid can cause itching, stinging, tingling, burning, tenderness, and skin dryness when applied to the skin. Usually the main solvent in cosmetic products. Propanediol is a natural alternative for the often usedand often bad-mouthed propylene glycol. Tretinoin and Azelaic Acid. Tretinoin is synthesized from beta-carotene.The beta-carotene is firstly cleaved into beta-carotene 15-15'-monooxygenase through site 1 double bond oxidized to epoxide.The epoxide is attacked by water to form diol in site 1. We Balance Nature and Science to provide Life Changing Benefits. Retinol Vs Retin-A: Whats The Difference? It's produced sustainably from corn sugar and it's Ecocert approved. I had some on my right cheek, some on my left cheek and one on my forehead. Store this medication at 68F to 77F (20C to 25C) and away from heat, moisture and light. Ngay c m bu cng c th p dng. Tretinoin (a metabolite of vitamin A) is the gold standard anti-aging ingredient that is also FDA-approved (and it's the only one so far!) Heres The Truth. Alpha Arbutin with Niacinamide: Alpha Arbutin and niacinamide serum are both water-based lightweight serums that can blend quite well. A super commonly used thickener and emulsion stabilizer. BeautySparkReview provides content of general nature that is designed for informational purposes only. Thanks to inflammation soothing properties, azelaic acid can be an excellent option for people looking to treat acne and rosacea. It's a type of lipid, a so-calledsphingoid base that can be found naturally in the upper layer of the skin. In fact, the niacinamide can actually help to reduce the irritation from the tretinoin! However if youre a new acid-user and want to give these two actives a shot, please do well to contact your board-certified dermatologist first (for advice whether or not to use them). Hyperpigmentation Azelaic acid can effectively treat postinflammatory hyperpigmentation - dark spots or patches on the skin that result from acne lesions, aging and prolonged . A helper ingredient that helps to makethe products stay nice longer, aka preservative. It is published by the Personal Care Product Council. Azelaic acid is a safe and proven acne treatment: In two studies, 20% azelaic acid cream was shown to be more effective than 0.05% tretinoin cream and better tolerated. An Ecocert-approved, natural preservative that counts as gentle and non-irritating to the skin. How it works: Share your skin goals and snap selfies. Your dermatology provider prescribes your formula. In my own case, i had some ugly-looking minor acne breakouts. The goopy stuff between our skin cells is called extracellular matrix that consists mainly of lipids. Well, we shall know about that. And ceramides are about 50% of those lipids (the other important ones are cholesterol with 25% and fatty acids with 15%). When used correctly, tretinoin and niacinamide can help to improve signs of acne, treat and prevent acne and smooth textural irregularities. Has antimicrobial and cell-communicating properties and is considered to be part of the skin's natural defence system. Since tretinoin is only available with a prescription, youll need to either start a chat with your Curology provider or visit an in-person medical provider. Both niacinamide and azelaic acid reduce redness and inflammation, help brighten skin and fade hyperpigmentation. I ordered the Niacinamide, azelaic acid, and vitamin C serums, and have been applying the C first followed by Niacinamide and azelaic acid mixed together. In rarer cases, swelling, rashes, hives, and difficulty breathing have been reported. But still endeavor to maintain the every-other-day application technique and not everyday. Azelaic acid is used topically in the management of acne vulgaris, rosacea and other inflammatory skin conditions. Retinol is a weaker retinoid as compared to tretinoin, which is an advantage to sensitive skin individuals. Step 4: Apply your moisturizer. It was a sweep-off. Along with ceramides 4 and 7, they also play a vital role in epidermal integrity and serve as the main storage areas for linoleic acid (a fatty acid that's alsovery important for barrier repair). Azelaic acid occurs naturally in some whole grains, but its generally safe to use topically for those with celiac disease or gluten sensitivities. Apply any other skin care products that are compatible with tretinoin such as Green Tea Antioxidant Skin Therapy and Daily Moisturizing Face Cream. A 6 month study involving 289 people found that 20% Azelaic Acid cream and 0.05% Tretinoin were "equally effective" against acne. . Azelaic acid is an antioxidant naturally produced on your skin, and its lab-engineered form is available as a gel, foam, or cream. Mirror mirror, on the wall, whats one of the most versatile skincare ingredients of them all? also, i use 15% azelaic acid, even though some people think it is irritating. Therefore, after an intensive and rigorous research, I decided to use niacinamide and azelaic acid together on my skin to put them to the test. A prescription from a medical provider (like your Curology provider!). Available from: https://www.ncbi.nlm.nih.gov/books/NBK557478/. So apply whichever product is thinner first, followed by the thicker product. Were here to break down five popular skincare ingredients, including what they do and how you can add them to your routine. Warning: This ingredient list belongs to a topical product regulated as medicine and uses different ingredient listing rules than regular cosmetics. Some of these ingredients are ones that your Curology provider can potentially prescribe to you. Theres also some evidence that suggests topical niacinamide may decrease sebum, or oilso if youre concerned about excess oil on some parts of your face, this might be a great ingredient to explore! Tretinoin + Niacinamide = A Dream Team for acne, scarring, pigmentation and aging. Monday-Friday: 9am-5pm Retinoic acid irritates the skin and causes the cells of the skin to grow (divide) and die . Combined with polyacrylate-13 and polysorbate 20, it forms a very effective tickener-emulsifier trio. .css-1p4obbr{color:#524D6E;-webkit-text-decoration:underline;text-decoration:underline;border-bottom:none;}.css-1p4obbr:hover,.css-1p4obbr:focus{color:#706D87;}Niacinamide, bakuchiol, CBD, even watermelonthere are so many buzzy ingredients saturating the market nowadays that it can be tricky to know where to start. It works even better when combined with its pal, Ceramide1. How to layer other skin care products with tretinoin at bedtime. In the experimental test, I used The Ordinary Niacinamide 10% + Zinc 1% Serum and Azelaic Acid Suspension 10%, for two weeks, and have decided to share my experience with these duo-actives. But worry not! A handy white powder that magically converts a liquid into a nice gel formula. Well, Ive been a long-time acid-user, (even though I have a sensitive skin), I technically know my way around acids and how to properly use them to avoid inflammatory-irritation. Its main job in skincare products is to moisturise the skin. By this I mean, use azelaic acid in the morning, while you use retinol at night but still maintain the every-other-day application method. Retinoids + AHA/BHA. Bottom line. Azelaic acid is a tyrosinase inhibitor which means that it prevents the activity of the tyrosinase enzyme that is essential for the production of melanin. It also stimulates collagen and production. Otherwise, tretinoin may not work properly or skin irritation might occur. Like what you just read? . If you wanna become a real HA-and-the-skin expert you can read way more about the topic at hyaluronic acid(including penetration-questions, differences between high and low molecular weight versions and a bunch of references to scientific literature). Take care and good luck. Tretinoin, also called all-trans-retinoic acid (ATRA), is a naturally occurring derivative of vitamin A (or retinol) that increases cell turnover. Ok, so now we know what ceramides are, let's see what they do in our skin: research shows clearly that they play a super important role in keeping the skin barrier healthy and the skin hydrated. Just sign up or start a chat with your provider to get started! How To Tell The Difference, 10 Best Vitamin C Face Creams For Skin Brightening & Anti-Aging Benefits, The Ordinary Vs Paulas Choice Azelaic Acid (Which Is Best? There is emerging research about Phytosphingosine that shows that it has antimicrobial and cell-communicating properties and is considered part of the skin's natural defense system. A natural corn sugar derived glycol. Like, zayum gurl! Found naturally in food (e.g., meat, dairy products, legumes, nuts, seeds, green leafy vegetables, fortified grains, etc. Ceramides make up 50% of the goopy stuff that's between our skin cells and play a super important role in having a healthy skin barrier and keeping the skin hydrated. To treat acne marks, Lorscher recommends products with niacinamide, azelaic acid, and alpha hydroxy acids. As always, apply the thinner product first, followed by the thicker product. Well, the answer is probably a no, but they do work to some extent. I'm Anselem Ukandu a passionate skincare-lover, writer and beauty editor with undying love for skincare and everything about it. Tiny-winy (micron sized) spheres that store emollient safflower seed oil and vitamin E. Oleosomes are both natural emulsifiers and time-released delivery systems that give the skin long-lasting moisture. There are also different brand names for Tretinoin- Retin A, Micro-A, Stieva-A, Renova, and Retrides to name a few. Shes on a mission to tell you what works and what doesnt do you can save time and money and get the skin of your dreams. Available: https://go.drugbank.com/drugs/DB00548. All my acne-breakouts were all gone!. Plus, some ingredients, like benzoyl peroxide actually render the tretinoin ineffective. A randomised investigator-blind parallel-group study to assess efficacy and safety of azelaic acid 15% gel vs. adapalene 0.1% gel in the treatment and maintenance treatment of female adult acne. You can use tretinoin and niacinamide together without any issues or worries of irritation. . The clinical benefit of the topical acne treatments azelaic acid, salicylic acid, nicotinamide, sulphur, zinc, and alpha-hydroxy acid is unclear. Ceramides get quite a lot of hype recently and good news: there is a reason for that. With years of professionalism and practice in the beauty industry, I've written hundreds of inspiring beauty tips expert-backed with facts and advices from board-certified Dermatologists, Estheticians and Cosmetologists. You can start from 0.025 or 0.05% tretinoin and 5 or 10% azelaic acid to ease your way into these acids and to allow your skin gradually build tolerance or get accustomed to them. Currently using a Dermatica blend of tretinoin 0.05%, niacinamide 4% and 1% Clindamycin. ingredients Tretinoin 0.05% + Azelaic acid 15% A real oldie but a goodie. We wrote way more about ceramides at ceramide 1, so click here to know more. Niacinamide holds anti-inflammatory properties and is used topically to manage a variety of skin conditions including bullous pemphigoid, IgA bullous dermatosis, acne vulgaris, and pruritus (itching). Fluocinolone, hydroquinone, and tretinoin topical may also be used for purposes not listed in this medication . Also-called: All-Trans-Retinoic Acid, Form of Retinoids | What-it-does: cell-communicating ingredient. is drying. It is used on the skin in the treatment of mild to moderate acne and on skin that has been damaged by excessive exposure to the sun. I KNOW RIGHT?! ), niacinamide is a precursor of the cofactors niacinamide adenine dinucleotide (NAD) and niacinamide adenine dinucleotide phosphate (NADP). I used Azelaic Acid (Finacea) after pregnancy to help clear melasma and was happy with it, but I was breastfeeding at . A study shows that a nail treatment liquide with 2% panthenol could effectively get into the nail and significantly increase the hydration of it. Curious about how to layer 3 popular actives? So, for the sake of your skin, limit tretinoin use at night-time only. You can separate the two products in your routine, depending on your preferences. Together with ceramides and fatty acids, they play a vital role in having a healthy skin barrier and keeping the skin hydrated. . This encouraged me, I had to keep up with the treatment religiously till the second week (week 2), boom!! Step 3: Apply tretinoin cream all over your face. One more thing: the water used in cosmetics is purified and deionized (it means that almost all of the mineral ions inside it is removed). Once inside the skin, it hydrates, but not from the outside - putting pure water on the skin (hello long baths!) A typeof ceramidethat can be found naturally in the upper layer of the skin. If youre using tretinoin gel and moisturizer, apply the tretinoin gel, wait a few minutes then follow with the niacinamide moisturizer. Can You Use Niacinamide With Salicylic Acid? If HA does not tell you anything we have a super detailed, geeky explanation about it here. For example, if youre using a niacinamide serum and a tretinoin cream, use the niacinamide serum first, followed by the tretinoin cream. If that wasnt enough panthenol is also useful in nail and hair care products. Niacinamide is known to promote collagen production that makes the skin Shed dead skin cells. In spite of this, if you search for "hyaluronic acid vs sodium hyaluronate" you will find on multiple places that sodium hyaluronate is smaller and can penetrate the skin better. Good old water, aka H2O. Whats even better is that you can use both of these ingredients together for maximum results without any issues or side effects. It normalizes keratinization and makes the pores produce less sebum. The Ordinary Natural Moisturizing Factors + HA, You can read my experimental-comparison review between The Ordinary & Paulas Choice azelaic acid 10%, I Used Niacinamide & Lactic Acid Together Heres My Review, I Used Niacinamide And Azelaic Acid From The Ordinary Brand & This Happened, Skin Purging Or Breaking Out? Can You Use Salicylic Acid And Niacinamide Together? You looking GOOD. Azelaic Acid is effective during all stages of acne 1: it reduces active acne, it helps clear up the redness, scarring, and hyperpigmentation that acne can cause, and it keeps acne bacteria at bay once your skin has healed. Azelaic Acid Vs Benzoyl Peroxide: Is One Better Than The Other? Learn how popular skincare ingredients like Azelaic acid, Niacinamide, Retinol, Salicylic acid, and Tretinoin can help treat acne, anti-aging, and hyperpigmentation, and more common skin concerns. The short answer is yes, you can use tretinoin and niacinamide together! Tretinoin's side effects can include all mentioned above, as well as the potential for exacerbating existing skin conditions you're already . A mild, natural preservative that usually comes to the formula together with its other mild preservative friends, such as Benzoic Acid and/orDehydroaceticAcid. All acne breakouts wiped-off without a trace. Its not strong enough to be used in itself so its always combined with something else, often with potassium sorbate.