", "Thank you very much for such a fast shipping. This means that we guarantee the purity and quality of this product. If youre unsure what NAD is, see above. Functions of hyaluronic acid include hydration, lubrication of joints, and the framework for blood vessel formation. (1-5), Whilst more often used for the above reasons, fisetin has also been shown to reduce depression, boost serotonin levels and boost hair growth. ", "I take NMN with water and now my headaches are gone. ", "Really fast delivery. I feel better overall. SureSleep contains 3 active ingredients to help get you to sleep, stay asleep, and benefit from the lack of fatigue afterwards. Our company address is: We ship worldwide. ", Each serving has 200mg of hyaluronic acid, Each serving has 1000mg of trans-resveratrol, We recommend this product is taken alongside our Pure Resveratrol, SIRT6Activator and Pure TMG. There are many varieties of seaweed available on the market, and the end product they produce differ in their chemical formulas. Finding ways to boost your NAD levels has become central to longevity. ", "I'm happy with the product. This is how we can guarantee the purity of your product to your door. ", "I just received my first two jars of hyaluronic acid and am very anxious to give it a go. It has been proven that oral supplementation of hyaluronic acid reduces wrinkles and results suggest that higher molecular weight has even more of an impact than other molecular weights. ", "I started to take NMN and hyaluronic acid. There are no endotoxins in this product. (5-6) NMN reduces the physical and neurological decline associated with ageing. To understand the science behind this, please see our Science page. Great customer service and love the products. However, daily hyaluronic acid supplementation moisturises your skin and makes it healthy. Those lacking in sleep are more likely to be overweight, have disrupted appetites, lose empathy, have more inflammation, have a low immune system, be depressed and suicidal, have impaired brain function and are more susceptible to heart problems. (1) Cutting your calorie intake by 15% whilst also using supplements can protect against cancer, diabetes and dementia. It is vital in the KREBS cycle (energy) and it aids the mitochondria (power packs of the cell). (1-13), (1), (2), (3), (4), (5), (6), (7), (8), (9), (10), (11), (12), (13), Berberine has anti-cancer, anti-inflammatory and antibacterial properties. Sometimes referred to as betaine, TMG has anti-inflammatory properties, can boost your exercise performance and protects both your liver and your heart. (10)(11)(12)(13)(14). I felt not tired and not sleepy even! Oxidative stress can damage all components of the cell, including DNA. (1)(2), The fuel that Sirtuins use is NAD, so to boost NAD levels we provide NMN. (12-14), (1), (2), (3), (4), (5), (6), (7), (8), (9), (10), (11), (12), (13), (14). (6-7). Always great service from DoNotAge. (15) Hyaluronic acid has a remarkable hydration capacity, and a lack of it causes reduced extracellular space volume in the brain. That depends on your location but is calculated for you at checkout. Sirtuin 6, or SIRT6, is a longevity gene. (6-11), (1), (2), (3),(4), (5), (6), (7) , (8) , (9) , (10), (11), Each serving has 1000mg of trans-resveratrol, Quercetin is a flavonoid that the human body cannot produce. Stealing ours. The best advice is to ensure you are logged in to www.donotage.org before purchasing. (7)(8), Magnesium slows dementia and reduces your chances of cancer. This product is suitable for vegans. Hyaluronic acid counteracts aging processes by its anti-inflammatory and radical scavenging properties. (1)(2)(3), Exercise can boost your NAD levels, increase the size of your brain and in turn, boost our memory. The journey to you will take around 48 hours depending where you live, which is far less than the 16 days for the product that is tested. Thank you for the product, I will continue to use! I am very satisfied with DoNotAge. ", "I am so happy that you exist and sell the high quality products that you do. ", "I'm happy with the product. In particular, they keep pushing the pricing of bulk NMN lower, and reduced their shipping rates to the US. Thus it seems the more high molecular weight hyaluronic acid, the less likely the cancer risk. Taking hyaluronic acid alleviates dry skin. SIRT6 enhances DNA double strand break repair under oxidative stress. NAD is crucial for telomeres. Thanks very much for everything and the extra presents!! Removing senescent cells is important for health as we age. In the body it is a precursor to NAD. Please note that for EU orders we ship from our base within the EU Customs Union so you do not pay any taxes or fees. All reviews are published without moderation. It has shown promise in inhibiting MTOR, activating AMPK, protecting stem cells, healthy bones and even with collagen production. When I finally discovered your shop it was amazing, because I have all I need in just one place. This space is vital for brain function. (2), Resveratrol has similar effects on your body as a calorie restricted diet. "I choose DONOTAGE because of a lot of good references and the third party analysis you show. We use dedicated people and clever technology to safeguard our platform. NAD is a wonderful discovery and extremely important for ageing. To understand the science behind this, please see our Science page. We recommend this product is taken alongside our Pure Resveratrol, SIRT6Activator and Pure TMG. The product came well packaged and in a decent time frame. I also took Quercetin to boost my immune system against allergies! It significantly increases time in bed, total sleep time and sleep efficiency total. Will keep this rating under review and change as appropriate.Have upped to five stars as they really made an effort to sort this out and follow up afterwards. They are trying to put this right. Activating SIRT6 may provide broad tumor suppressant and health promoting benefits. Furthermore, long-lived animal species have more active SIRT6. Fisetin has also shown the potential to fight multiple cancers, protect the brain from strokes, reduce inflammation, reduce seizures, support the immune system and fight many other diseases. Questions regarding product are answered promptly. (4)(5)(6)(7) Additionally, fasting has been proven to be a good way to lose weight, whilst keeping your muscle mass. the yearly subscription is too much for us to afford so we just buy every few months. The Do Not Age Quality Guarantee means that your product quality is guaranteedto your door, no matter where you live in the world. We can do this because once the products are manufactured, we refrigerate them all. Thanks very much for everything and the extra presents!! ", "Thank you for your great products and service! - I know who I would prefer to trust, The products are outstanding as well as the customer service. ", "My experience with Do Not Age is great! In basic terms the theory is that the higher your hyaluronic acid, the more moisture your skin will retain and therefore less aging of the skin. ", "I just received my first two jars of hyaluronic acid and am very anxious to give it a go. My resting pulse rate dropped from 50 to 37 bpm. Anyone can write a Trustpilot review. Companies can ask for reviews via automatic invitations. I felt not tired and not sleepy even! Almost all of our products are vegan. Finally, when we ship your product to you, it has been kept refrigerated right up until it is collected by the courier. It is not a placebo effect.My entire exercise regimen improved. (4)(5) It seems that interval training has superior health benefits to other types of exercise. 2022 Trustpilot A/S. The total time the product has been unrefrigerated is 16 days. ", "I just tried the NMN powder and ooh boy I could feel the energy. (3). Many reasons. Not everything can always go smoothly but when it didn't, the staff and management at Do Not Age rose to the occasion to make it right. The prices are unbeatable for such high-quality products! (4), Valerian root has long been used to induce sleep, and for good reason. Your brain uses sleep to run checks its hormones and enzymes are in balance. ", "My experience has been great! ", "My wife and I have been using for 7 months now. (4, 5), Just as NAD decreases with age, CD38 increases as we age. (1-7), Resveratrol supplementation has been shown to increase lifespan. As always, we over deliver to provide you with even more value, but this also covers against mishaps. (5)(6), Nicotinamide mononucleotide, or NMN for short, is a derivative of Vitamin B3. We recommend this product is taken alongside our Pure Resveratrol, SIRT6Activator and Pure TMG. This natural bodily process helps us to get rid of old and damaged cells, and create new, healthy ones. I now have more energy and dont have to take any naps during the day! Senescent cells accumulate as we age. Firstly, please clear your cookies and cache and then restart your browser. ", FREE DELIVERY USA $100 / UK 50 / EU 300 / WORLDWIDE $400, ONLY PRODUCTS WHOSE PURITY GUARANTEED TO YOUR DOOR. (1) CD38 is inhibited by both Quercetin and Apigenin. What we are trying to achieve is the resveratrol activating sirtuin 1 (thats a good thing), SIRT6Activator activating sirtuin 6 (thats a very good thing!) (2-4), Activating AMPK can be achieved via both lifestyle, for example high intensity exercise, and via supplementation, for example berberine. NAD, or nicotinamide adenine dinucleotide, is so important to life, that without it, you would die within seconds. (2)(3)(4)(5)(6), 79% of us do not get enough magnesium, and magnesium deficiency can induce a wide range of clinical complications, including painful muscle spasms, osteoporosis, fibromyalgia, irregular heartbeats, and headaches. This product is suitable for vegans, and as always, has no fillers. Our products are manufactured and stored in cool, dark and dry environments. Once a cell becomes senescent, it remains active and can release harmful substances that may cause inflammation and damage to nearby healthy cells, this is why they are often called zombie cells. Here are 8 tips for writing great reviews. I feel better overall. However, please feel free to contact us on hello@donotage.org if you require any assistance. ", "I am so happy that you exist and sell the high quality products that you do. (1), Apigenin can reduce anxiety without negative effects, as well as protect the brain from decline. We recommend TMG, particularly for those that take NMN. Some keys for quality sleep are drinking enough water, having enough melatonin and reducing blue light in the evening. I feel better overall. The energy boost is no joke. The delivery was on time and I'm really happy I don't have to mix powders anymore", Each serving has 200mg of hyaluronic acid, Each serving has 1000mg of trans-resveratrol, We recommend this product is taken alongside our Pure Resveratrol, SIRT6Activator and Pure TMG. (10-18), One of spermidines most prominent benefits is the effect on the brain. They improved immune response to flu vaccine in the elderly, reduced inflammation, and improved survival of cancer patients undergoing chemotherapy. Autophagy can be activated by performing extended fasts (over 48 hours) or supplementing with ingredients such as spermidine. Berberine plays an important role in metabolism, lowering your LDL cholesterol and triglycerides, and protecting you from heart disease. ", "My experience has been great! There are many poor-quality products around which simply aren't worth taking. Ive been taking do not age NMN for about a month and a half, unfortunately I feel no difference than before.. still over tired and pushing myself to work out. After this time, it is then shipped from the UK to the USA to be tested for purity and heavy metals. 5 starsthe shipment is always fast to canada and the products are high qualityi hope to take them all one dayi never pay import taxes either so they must ship locally, do not age is good brand. We will try our best to accommodate any changes required, however please be aware that once your order has shipped, it cannot be changed. A lack of hyaluronic acid has led to seizures and diminished brain activity. The industry is filled with people trying to make a quick buck and they will use any means to get it, including using our product names and likenesses. So boosting NAD levels is less effective when CD38 is too high. Nicotinamide mononucleotide (NMN) supports healthy NAD+ levels and this has resulted in amazing results for Do Not Age NMN users. There are no endotoxins in this product. Finally, when we ship your product to you, it has been kept refrigerated right up until it is collected by the courier. and NMN increasing the fuel for those sirtuins, so that they can do their healthy work. There are many poor-quality products around which simply aren't worth taking. It also causes significant improvements in skin hydration, wrinkles and elasticity. Thanks very much for everything and the extra presents!! The most potent senolytic we know of is fisetin. This means that supplementing with high molecular weight hyaluronic acid is beneficial for your joint and skin health. I felt not tired and not sleepy even! Mistakes are rare, but when they do happen it is easier for us to have already given you extra product than to send another item. All of our products are produced to GMP and ISO9001 standards. Your mitochondria, which are responsible for energy production, use NAD as fuel. I got charged for duties import tax. Laboratory studies suggest that it can prevent the growth of cancer cells and has antiviral, neuroprotective, and immune-modulating effects. The effect will keep me ordering more before my stock runs out. I recommend DoNotAge to everyone because of the transparency, quality and fast deliveries. The package came quite quick, dodged a bullet! (26, 27), (1), (2), (3), (4), (5), (6), (7),(8), (9), (10), (11), (12), (13), (14), (15), (16), (17), (18), (19), (20), (21), (22), (23), (24), (25), (26), (27), Sleep is a vital component of health, and the majority of adults struggle with it. (2), Sirtuins are a family of proteins that keep your cells healthy and promote DNA repair. It may also protect telomere length. Nicotinamide mononucleotide (NMN) supports healthy NAD+ levels in humans and this has resulted in amazing results for Do Not Age NMN users. It has been shown to relieve oxidative stress, reduce cancers, protect against UV damage and sunburn, protect the liver and reduce viral load.