Usually avoid combinations; use it only under special circumstances. View more. 46 ratings on Drugs.com. Tell your doctor if this medication stops working well (for example, you have more frequent or worsening chest pain). if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking isosorbide. Take extra precautions to avoid falling during your treatment with isosorbide. Consult your doctor for more details. Although not all of these side effects may occur, if they do occur they may need medical attention.Check with your doctor immediately if any of the following side effects occur:Less commonAbnormal heart soundabsence of or decrease in body movementarm, back, or jaw painblack, tarry stoolsbladder painbleeding after defecationbleeding gumsblood in the urine or stoolsblurred visionbody aches or painburning while urinatingburning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelingschest pain or discomfortchest tightness or heavinesschillscold sweatscoldsconfusionconvulsionscough or hoarsenessdecreased urinediarrheadifficult or labored breathingdifficult, burning, or painful urinationdilated neck veinsdizzinessdizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting positiondry mouthear congestionextra heartbeatsfaintingfast, slow, irregular, pounding, or racing heartbeat or pulsefever or chillsflu-like symptomsfrequent urge to urinatefrequent urinationgeneral feeling of discomfort or illnessheadacheheadache, severe and throbbingheart murmurincreased need to urinateincreased sweatingincreased thirstincreased volume of pale, dilute urineirregular breathingitching, pain, redness, or swelling on the legjoint pain, stiffness, or swellinglightheadednessloss of appetiteloss of voicelower back, side, or stomach painmuscle aches and painsmuscle crampsnasal congestionnausea or vomitingnervousnessnumbness or tingling in the hands, feet, or lipspain or discomfort in the arms, jaw, back, or neckpain, tension, and weakness upon walking that subsides during periods of restpartial or slight paralysispassing urine more oftenpinpoint red or purple spots on the skinpounding in the earsrunny noseshakiness in the legs, arms, hands, or feetshiveringsneezingsore on the legsore throatsudden decrease in the amount of urinesweatingswellingswelling of the face, fingers, feet, or lower legstightness in the chesttrembling or shaking of the hands or feettrouble sleepingtroubled breathinguncomfortable swelling around the anusunusual bleeding or bruisingunusual tiredness or weaknessvomiting of blood or material that looks like coffee groundsweaknessweight gainRareBluish-colored lips, fingernails, or palmsdark urinepale skinrapid heart rateGet emergency help immediately if any of the following symptoms of overdose occur:Symptoms of overdoseBlurred or loss of visionbulging soft spot on the head of an infantchange in consciousnesschange in the ability to see colors, especially blue or yellowcold, clammy skindisturbed color perceptiondouble visionfeeling of constant movement of self or surroundingshalos around lightsheadache, severe and throbbingloss of consciousnessnight blindnessoverbright appearance of lightsparalysissensation of spinningtunnel visionSome side effects may occur that usually do not need medical attention. This should pass after a few days. Some don't work well with prescription medicines. 8600 Rockville Pike With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. The American Society of Health-System Pharmacists, 4500 East-West Highway, Suite 900, Bethesda, Maryland. Data were assessed for carryover and time effects. It can make you really dizzy. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital. If you do not remember until your next dose is nearly due, then leave out the forgotten dose and take your next dose when it is due. No, that's not true all the time. It has a very short duration of action and may not be suitable for some people. Isosorbide-5-mononitrate ISMN usually begins acting within 30 minutes and its effects last six to eight hours. https://naturalmedicines.therapeuticresearch.com. View World Anti-Doping Agency classifications, Prevention of Thromboembolism in Atrial Fibrillation, Prosthetic Heart Valves - Thrombosis Prophylaxis, Prosthetic Heart Valves - Mechanical Valves - Thrombosis Prophylaxis, Revascularization Procedures - Prophylaxis. Breastfeeding:There is data that nitrates are excreted in breast milk and may cause methemoglobinemia in infants. Do not stop taking isosorbide without talking to your doctor. URL of this page: https://medlineplus.gov/druginfo/meds/a682348.html. Never give it to other people even if their condition appears to be the same as yours. Isosorbide mononitrate helps to prevent angina chest pain from developing. Enter other medications to view a detailed report. It works more slowly and lasts for about 12 hours, so you only need to take it once a day. During pregnancy, this medication should be used only when clearly needed. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Do not drink alcohol while taking View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions. My blood pressure, cholesterol and pulse are all normal and I have no chest pains, shortness of breath or other heart problem symptoms. What special precautions should I follow? Isosorbide mononitrate tablets and capsules are not suitable to take to treat the pain of an angina attack. It is not intended as medical advice for individual conditions or treatment. Accessed Sept. 7, 2022. We don't support your browser. tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Symptoms of overdose may include: slow heartbeat, vision changes, severe nausea/vomiting, sweating, cold/clammy skin, bluish fingers/toes/lips. Bauer B (expert opinion). Prescribed for Angina, Anal Fissure and Change positions slowly until your body is used to the medication. Isosorbide may cause other side effects. Other medications may be prescribed by your doctor for these conditions. You may opt-out of email communications at any time by clicking on Synthroid (levothyroxine) Tylenol (acetaminophen) Vitamin B12 (cyanocobalamin) Vitamin C (ascorbic acid) Vitamin D3 (cholecalciferol) Isosorbide mononitrate disease interactions There are 7 disease interactions with isosorbide mononitrate which include: AMI anemia hemodialysis hypotension intracranial pressure hypertrophic cardiomyopathy glaucoma This is called tolerance, and it cannot be fixed by raising the dose of the medication. The .gov means its official. This content does not have an Arabic version. Aspirin relieves pain and inflammation and helps to thin the blood. Unauthorized use of these marks is strictly prohibited. Accessed Sept. 7, 2022. Always consult your healthcare provider. You could also spray your face with cool water or sip non-alcoholic cold or iced drinks. About one-half of adults in the United States say they have used one or more supplements in the past 30 days. 2010; doi:10.1016/j.jacc.2009.07.074. https://naturalmedicines.therapeuticresearch.com. Take this medication by mouth as directed by your doctor, usually twice a day. Your health care provider and pharmacist can help you stay away from unsafe interactions. However, you should not flush this medication down the toilet. This content does not have an Arabic version. Things to remember when you fill your prescription. Elsevier; 2021. https://www.clinicalkey.com. Compare a few possible alternatives below. This site complies with the HONcode standard for trustworthy health information: verify here. Is isosorbide mononitrate (Monoket) the same as nitroglycerin (Nitrostat)? Natural Medicines. Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. Receive price alerts, news, and other messages from GoodRx about isosorbide mononitrate (Monoket) and other healthcare topics and relevant savings offers. Accessed Sept. 7, 2022. Commonly reported side effects include: See also: isosorbide mononitrate side effects in more detail. In: Textbook of Natural Medicine. Mayo Clinic; 2021. These headaches may be a sign that the medication is working as it should. Nitroglycerin works very quickly to widen your blood vessels and help your heart pump blood during a heart attack. It also may keep some medicines from working as well as they should, such as: If your health care provider tells you it's OK to use an herbal supplement along with medicine, be careful. Mehta D. Botanical medicines. Drug information provided by: IBM Micromedex. Journals of the American College of Cardiology. Consult your doctor before breast-feeding. If you have an underactive thyroid gland. Prescription and OTC Aspirin relieves pain and inflammation and helps to thin the blood. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Accessed Sept. 7, 2022. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Tolerance is more likely to happen if you don't take your dose at the same time every day. To help you remember, take it at the same times each day. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Use this medication regularly to get the most benefit from it. If you notice any other effects, check with your healthcare professional. If you miss a dose, take it as soon as you remember. Cleophas TJ, Niemeyer MG, Zwinderman AH, van der Wall EE. A very serious allergic reaction to this drug is rare. You may report side effects to Health Canada at 1-866-234-2345. All rights reserved. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Nitrate-Induced Headache in Patients with Stable Angina Pectoris: Beneficial Effect of Starting on a Low Dosage. The effects of this exposure on a nursing infant are unknown. Botanical medicine A modern perspective. Isosorbide mononitrate (Monoket) is a nitrate vasodilator. Otherwise, call a poison control center right away. Stopping isosorbide mononitrate (Monoket) suddenly can cause you to have a worsening of your chest pain. Theyre fast, easy-to-use and free! If you have any problems with the way your liver works, or any problems with the way your kidneys work. Alcohol will increase the risk of you experiencing side-effects such as feeling dizzy and light-headed. Isosorbide mononitrate, sold under many brand names, is a medication used for heart-related chest pain ( angina ), heart failure and esophageal spasms. It can cause your blood pressure to become dangerously low. Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. This medicine is for you. What should I know regarding pregnancy, nursing and administering Isosorbide Mononitrate to children or the elderly? . Bookshelf It works to relax your blood vessels. For these reasons, before you start taking isosorbide mononitrate it is important that your doctor knows: Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. Talk to your provider if you notice your chest pain starts to get worse. Can isosorbide mononitrate cause problems? Higher dosages are associated with stomach irritation and Isosorbide mononitrate helps to prevent angina chest pain from developing. View all The dose is according to the body weight and severity of the condition. To use the sharing features on this page, please enable JavaScript. Anti-ischemic and anti-anginal effects of controlled-release and conventional isosorbide-5-mononitrate in stable angina pectoris. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program. If you become pregnant while taking isosorbide, call your doctor. Murray MT. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. There are no data on passage of isosorbide mononitrate in human milk, but some excretion seems likely. It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. Healthcare data is obtained from a number of sources including the Food and Drug Administration (FDA). Disclaimer. Read our editorial policy. Lyrica and Metoclopramide drug interaction, Calcitriol and Metoclopramide drug interaction. Generic alternatives may be available. Isosorbide extended-release (long-acting) tablets and extended-release capsules are used for the management of chest pain in people who have coronary artery disease. This medicine is available only with your doctor's . Isosorbide mononitrate has an average rating of Take the container with you, even if it is empty. Do not use medications containing isosorbide dinitrate while using isosorbide mononitrate. It is best not to drink alcohol while you are on isosorbide mononitrate. Pregnancy:Data on the use of isosorbide mononitrate during pregnancy are insufficient to be able to assess the possible harmful effect. https://naturalmedicines.therapeuticresearch.com. This activity describes the indications, action, and contraindications for isosorbide as a valuable agent in treating angina pectoris due to coronary artery disease, heart failure with reduced . We study 23,548 Isosorbide mononitrate users. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Don't drink alcohol while taking isosorbide mononitrate (Monoket). Your doctor may tell you to take a pain reliever to treat your headaches. [2] It is taken by mouth. Trapidil is as effective as isosorbide-dinitrate for treating stable angina pectoris: a multinational, multicenter, double-blind, randomized study. Good at preventing chest pain caused by heart disease, Available as a generic version, making it less expensive, Long-acting version only needs to be taken once daily, Short-acting tablets have to be taken on a very specific schedule for the medication to work best. HHS Vulnerability Disclosure, Help Should I avoid certain foods while taking Isosorbide Mononitrate? Talk to your doctor if you are using marijuana (cannabis). Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Important information about all medicines, Notes on Isosorbide mononitrate dose and side-effects info, https://patient.info/medicine/isosorbide-mononitrate-elantan-imdur-isotard-monomax-tardisc-xismox, Manufacturer's PIL, Isosorbide mononitrate 10 mg tablets, Carmil XL; Chemydur XL; Elantan LA; Imdur; Isib XL; Ismo; Isodur XL; Isotard XL; Modisal XL; Monomax SR; Monomil XL; Nyzamac SR; Relosorb XL; Tardisc XL; Trangina XL; Xismox XL; Zemon XL, Tablets, modified-release (longer-acting) tablets, and modified-release (longer-acting) capsules, Ask your doctor or pharmacist to recommend a suitable painkiller. Unless your doctor tells you otherwise, continue your normal diet. This drug may make you dizzy. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: continuing ringing or buzzing or other unexplained noise in the ears, dull ache or feeling of pressure or heaviness in the legs, excess air or gas in the stomach or intestines, increased sensitivity of the eyes to sunlight, loss in sexual ability, desire, drive, or performance, pain or tenderness around the eyes and cheekbones, redness of the face, neck, arms, and occasionally, upper chest, redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid, redness, swelling, or soreness of the tongue, small clicking, bubbling, or rattling sounds in the lung when listening with a stethoscope, stomach bloating, burning, cramping, or pain, terrifying dreams causing sleep disturbances, uncontrolled twisting movements of the neck, white patches in the mouth, tongue, or throat.